Properties
Description
Tacedinaline, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC2, and HDAC3.
Molecular Formula
C15H15N3O2
Targets
HDAC1: 0.9 μM; HDAC2: 0.9 μM; HDAC3: 1.2 μM
Solubility
DMSO: 51 mg/mL (189.37 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Tacedinaline is used in research to explore its role in inhibiting histone deacetylase (HDAC) and its therapeutic potential in the treatment of cancer.