HDAC inhibitor Trichostatin A, Purity ≥98%

Synonym: 58880-19-6; Trichostatin A; TSA; Trichostatin A (TSA); Trichostatin; (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide; Antibiotic A-300; HDAC inhibitor

MDL: MFCD03848392
CAS Number: 58880-19-6
Compound CID: 444732

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Trichostatin A, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC.

Molecular Weight

302.4

Molecular Formula

C₁₇H₂₂N₂O₃

Targets

HDAC: 1.8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 20 mg/mL (66.13 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Trichostatin A is commonly used to explore the broad-spectrum inhibition of HDACs and its implications in cancer treatment and gene expression modulation.