HDAC inhibitor Tucidinostat, Purity ≥98%

Synonym: Tucidinostat; 1616493-44-7; Epidaza; HBI-8000; 743438-44-0; CS-055; (E)-N-(2-Amino-4-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide; HDAC inhibitor

CAS Number: 1616493-44-7
Compound CID: 12136798

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tucidinostat, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, and HDAC8.

Molecular Weight

390.42

Molecular Formula

C₂₂H₁₉FN₄O₂

Targets

HDAC1: 95 nM; HDAC10: 78 nM; HDAC11: 432 nM; HDAC2: 160 nM; HDAC3: 67 nM; HDAC8: 733 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 69 mg/mL (176.73 mM); Water: Insoluble; Ethanol: 2 mg/mL (5.12 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Tucidinostat, an HDAC inhibitor, is used in research to determine its effectiveness in treating hematologic malignancies and solid tumors.