Properties
Description
UF010, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC6, and HDAC8.
Molecular Formula
C11H15BrN2O
Targets
HDAC1: 0.5 μM; HDAC10: 15.3 μM; HDAC11: 44.5 μM; HDAC2: 0.1 μM; HDAC3: 0.06 μM; HDAC6: 9.1 μM; HDAC8: 1.5 μM
Solubility
DMSO: 47 mg/mL (173.33 mM); Water: Insoluble; Ethanol: 47 mg/mL (173.33 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
UF010 can be used in research focusing on its potential as an HDAC inhibitor and its effects on cell proliferation and apoptosis.
