HDAC inhibitor WT-161, Purity ≥98%

Synonym: WT-161; 1206731-57-8; WT161; CHEMBL5075729; N'-Hydroxy-N-[(E)-[4-(N-phenylanilino)phenyl]methylideneamino]octanediamide; (E)-8-(2-(4-(Diphenylamino)benzylidene)hydrazinyl)-N-hydroxy-8-oxooctanamide; HDAC inhibitor

CAS Number: 1206731-57-8
Compound CID: 44601455

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WT-161, soluble in DMSO and ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8.

Molecular Weight

458.55

Molecular Formula

C₂₇H₃₀N₄O₃

Targets

HDAC1: 8.35 nM; HDAC2: 15.4 nM; HDAC3: 51.6 nM; HDAC6: 0.4 nM; HDAC8: 1430 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 75 mg/mL (163.55 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.18 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

WT-161 can be used to explore its inhibitory effects on IKK and its potential therapeutic implications in treating cancers.