Hedgehog inhibitor GANT61, Purity ≥98%

Synonym: 500579-04-4; Hedgehog inhibitor; NSC136476; NSC-136476; GANT 61; GANT-61

MDL: MFCD14635408
CAS Number: 500579-04-4
Compound CID: 421610

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GANT61, soluble in ethanol and insoluble in water and DMSO, disrupts the hedgehog signaling pathway, which is a critical regulator of cell differentiation and development. It targets GLI1 (HEK293T cells expressing GLI1).

Molecular Weight

429.61

Molecular Formula

C₂₇H₃₅N₅

Targets

GLI1 (HEK293T cells expressing GLI1): 5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: Insoluble; Water: Insoluble; Ethanol: 11 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

GANT61 is a Hedgehog inhibitor studied for its role in blocking the Gli transcription factors, important in cancer research.