Properties
Description
GDC-0449, soluble in DMSO and insoluble in ethanol and water, disrupts the hedgehog signaling pathway, which is a critical regulator of cell differentiation and development.
Molecular Formula
C19H14Cl2N2O3S
Solubility
DMSO: 72 mg/mL (170.9 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC-0449 is investigated for its ability to inhibit hedgehog signaling, primarily in oncological studies.
