Properties
Description
Mebendazole, soluble in DMSO and insoluble in ethanol and water, disrupts the hedgehog signaling pathway, which is a critical regulator of cell differentiation and development.
Molecular Formula
C16H13N3O3
Solubility
DMSO: 5 mg/mL (16.93 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Mebendazole is a Hedgehog pathway inhibitor that is repurposed from its antiparasitic uses to explore cancer treatment strategies.