Properties
Description
Purmorphamine, soluble in warmed DMSO and insoluble in water and ethanol, disrupts the hedgehog signaling pathway, which is a critical regulator of cell differentiation and development. It targets smoothened (HEK293T cells).
Molecular Formula
C31H32N6O2
Targets
Smoothened (HEK293T cells): 1.5 μM
Solubility
Warmed DMSO: 4 mg/mL (7.68 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Purmorphamine is utilized to investigate its effects on activating the hedgehog signaling pathway for stem cell research.