Hedgehog inhibitor SANT-1, Purity ≥98%

Synonym: 304909-07-7; Hedgehog inhibitor; SANT 1; SANT1

MDL: MFCD01827306
CAS Number: 304909-07-7
Compound CID: 6878030

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SANT-1, soluble in DMSO and ethanol and insoluble in water, disrupts the hedgehog signaling pathway, which is a critical regulator of cell differentiation and development. It targets smoothened receptor.

Molecular Weight

373.5

Molecular Formula

C₂₃H₂₇N₅

Targets

Smoothened receptor: 1.2 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 21 mg/mL (56.22 mM); Water: Insoluble; Ethanol: 20 mg/mL (53.54 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SANT-1 is a Hedgehog pathway inhibitor used to understand the inhibition of the signaling related to various cancers.