Properties
Description
FG-2216, soluble in DMSO and insoluble in ethanol and water, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth. It targets PHD2.
Molecular Formula
C12H9ClN2O4
Solubility
DMSO: 48 mg/mL (171.02 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
FG-2216 acts as a HIF inhibitor, employed in research focusing on anemia and ischemic diseases.