Properties
Description
FG-4592, soluble in DMSO and insoluble in ethanol and water, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth.
Molecular Formula
C19H16N2O5
Targets
HIF α prolyl hydroxylase
Solubility
DMSO: 62 mg/mL (175.96 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
FG-4592, another HIF inhibitor, is investigated for its role in treating anemia, particularly related to chronic kidney disease.
