Properties
Description
PT2399, soluble in DMSO and ethanol and insoluble in water, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth.
Molecular Formula
C17H10F5NO4S
Solubility
DMSO: 81 mg/mL (193.17 mM); Water: Insoluble; Ethanol: 81 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
PT2399 is explored to specifically block HIF-2α, providing insights into its role in tumor growth and metastatic processes.