Properties
Description
PX-478 HCl, soluble in DMSO, water and ethanol, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth. It targets HIF-1α.
Molecular Formula
C13H20Cl4N2O3
Solubility
DMSO: 73 mg/mL (185.21 mM); Water: 73 mg/mL (185.21 mM); Ethanol: 73 mg/mL (185.21 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PX-478 HCl is utilized to target HIF-1α, aiding in the exploration of hypoxia-driven cancer growth and potential therapeutic interventions.