Properties
Description
Vadadustat, soluble in DMSO and ethanol and insoluble in water, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth.
Molecular Formula
C14H11ClN2O4
Solubility
DMSO: 59 mg/mL (192.37 mM); Water: Insoluble; Ethanol: 9 mg/mL (29.34 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Vadadustat is employed in investigating treatments for anemia by modulating HIF pathways to stimulate erythropoiesis.