Properties
Description
JIB-04, soluble in warmed DMSO and insoluble in water and ethanol, prevents the removal of methyl groups from histones, influencing gene expression by maintaining histone methylation.
Molecular Formula
C17H13ClN4
Solubility
Warmed DMSO: 22 mg/mL (71.24 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
JIB-04 is used to inhibit Jumonji family demethylases, facilitating research on cancer and epigenetic regulation.