Histone demethylases inhibitor ML-324, Purity ≥98%

Synonym: 1222800-79-4; ML 324; ML324; Histone demethylases inhibitor

CAS Number: 1222800-79-4
Compound CID: 44143209

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ML-324, soluble in warmed DMSO and warmed ethanol and insoluble in water, prevents the removal of methyl groups from histones, influencing gene expression by maintaining histone methylation. It targets JMJD2.

Molecular Weight

349.43

Molecular Formula

C₂₁H₂₃N₃O₂

Targets

JMJD2: 920 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 38 mg/mL (108.74 mM); Water: Insoluble; Warmed ethanol: 3 mg/mL (8.58 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

ML-324 can be used to inhibit KDM4 demethylases, aiding studies in gene expression and cancer.

Storage

Store at -20ºC.