Properties
Description
RG-6016, soluble in DMSO, water and warmed ethanol, prevents the removal of methyl groups from histones, influencing gene expression by maintaining histone methylation. It targets LSD1/KDM1A.
Molecular Formula
C15H22N2.2HCl
Targets
LSD1/KDM1A: 20 nM
Solubility
DMSO: 4 mg/mL (13.18 mM); Water: 53 mg/mL (174.76 mM); Warmed ethanol: 3 mg/mL (9.89 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
RG-6016 is an LSD1 inhibitor used for research into its role in cancer and neurodegeneration.
