Properties
Description
GSK744, soluble in warmed DMSO and insoluble in water and ethanol, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread. It targets HIV integrase.
Molecular Formula
C19H17F2N3O5
Solubility
Warmed DMSO: 33 mg/mL (81.41 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GSK744 is a long-acting HIV integrase inhibitor researched for preventing integration of viral DNA into the host genome, helping to impede HIV replication.