Properties
Description
MK-0518, soluble in DMSO and insoluble in ethanol and water, blocks the action of the integrase enzyme, which is crucial for the HIV virus to integrate its genetic material into the host cell’s DNA, thereby impeding the virus’s ability to replicate and spread.
Molecular Formula
C20H21FN6O5
Solubility
DMSO: 80 mg/mL (180.01 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
MK-0518 is studied for blocking HIV integrase, thereby preventing integration of viral DNA into the host genome.
