HIV protease inhibitor ABT-378, Purity ≥98%

Synonym: 192725-17-0; HIV protease inhibitor; ABT-378

MDL: MFCD22628840
CAS Number: 192725-17-0
Compound CID: 92727

Product Size

10 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ABT-378, soluble in DMSO and ethanol and insoluble in water, blocks the protease enzyme, essential for the maturation and replication of HIV, playing a key role in highly active antiretroviral therapy (HAART). It targets HIV protease.

Molecular Weight

628.8

Molecular Formula

C₃₇H₄₈N₄O₅

Targets

HIV protease: 1.3 pM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 116 mg/mL (184.48 mM); Water: Insoluble; Ethanol: 116 mg/mL (184.48 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

ABT-378 is used in research to inhibit HIV-1 protease, preventing viral protein processing and assembly.