Properties
Description
Amprenavir, soluble in DMSO and ethanol and insoluble in water, blocks the protease enzyme, essential for the maturation and replication of HIV, playing a key role in highly active antiretroviral therapy (HAART). It targets HIV protease and PXR.
Molecular Formula
C25H35N3O6S
Targets
HIV protease: 14.6 ng/mL; PXR
Solubility
DMSO: 15 mg/mL (29.66 mM); Water: Insoluble; Ethanol: 91 mg/mL (179.97 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Amprenavir serves as an HIV protease inhibitor, preventing the proteolytic cleavage of precursor proteins necessary for the production of infectious viral particles.