HMG-CoA reductase inhibitor, Rosuvastatin calcium, Purity ≥98%

Synonym: 147098-20-2; Rosuvastatin hemicalcium; Rosuvastatin calcium salt; Fortius; Rostar; Rovista; Rozavel; Suvikan; ZD4522; ZD 4522, calcium salt; Calcium; (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate; HMG-CoA reductase inhibitor

CAS Number: 147098-20-2
Compound CID: 5282455

Product Size

25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rosuvastatin calcium, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HMG-CoA reductase. The molecular weight of the compound is 501.5, and its molecular formula is C₂₂H₂₈FN₃O₆S·1/2Ca.

Molecular Weight

501.5

Molecular Formula

C₂₂H₂₈FN₃O₆S·1/2Ca

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 91 mg/mL (181.79 mM); Water: insoluble; Ethanol: insoluble; In vivo: 4% DMSO + 30% PEG 300 + dd H₂O, 9 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Rosuvastatin calcium plays a key role in reducing the risk of cardiovascular events, including heart attacks and strokes, by improving lipid profiles and stabilizing atherosclerotic plaques.