HMG-CoA reductase inhibitor, Simvastatin, Purity ≥98%

Synonym: 79902-63-9; MK 733; MK-733; MK733; Zocor; Synvinolin; Sinvacor; Denan; Lipex; Sivastin; Lodales; Cholestat; Simvastatine; Colemin; Medipo; Pantok; Simovil; Labistatin; Simvastatina; Simvastatinum; Velostatin; Coledis; Corolin; Nivelipol; Rendapid; Vasotenal; Zorced; Rechol; Zocord; Simvastatin (Zocor); Simvastatin lactone; Lipovas; Simcard; Simvacor; Simvoget; Simlup; Zosta; [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-Hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate; HMG-CoA reductase inhibitor

MDL: MFCD00072007
CAS Number: 79902-63-9
Compound CID: 54454

Product Size

50 mg; 100 mg; 200 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Simvastatin, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HMG-CoA reductase. The molecular weight of the compound is 418.57, and its molecular formula is C₂₅H₃₈O₅.

Molecular Weight

418.57

Molecular Formula

C₂₅H₃₈O₅

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 71 mg/mL (169.62 mM); Water: insoluble; Ethanol: 71 mg/mL (169.62 mM); In vivo: 2% DMSO + 30% PEG 300 + 5% Tween80 + ddH₂O, 9 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Simvastatin can be studied extensively for its potential therapeutic applications in the treatment of heart attacks, strokes, and other cardiovascular events by improving lipid profiles and preventing the progression of atherosclerosis.