Properties
Description
A-366, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets G9a/GLP.
Molecular Formula
C19H27N3O2
Solubility
DMSO: 62 mg/mL (188.19 mM); Water: Insoluble; Ethanol: 62 mg/mL (188.19 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
A-366 is employed in research to investigate the inhibition of H3K4 methyltransferases in gene expression.
