HMT inhibitor CM-579, Purity ≥98%

Synonym: 1846570-40-8; CM579; CM 579; Histone methyltransferase inhibitor

CAS Number: 1846570-40-8
Compound CID: 118613729

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CM-579 inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets DNA methyltransferase, DNMT1, DNMT3A, DNMT3B, and G9a.

Molecular Weight

492.65

Molecular Formula

C₂₉H₄₀N₄O₃

Targets

DNA methyltransferase: 32 nM; DNMT1: 1.5 nM; DNMT3A: 92 nM; DNMT3B: 1000 nM; G9a: 16 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

CM-579 can be used as an inhibitor of both G9a and DNMT1 for studying epigenetic modifications.