Properties
Description
CPI-1205, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression.
Molecular Formula
C27H33F3N4O3
Solubility
DMSO: 90 mg/mL (173.55 mM); Water: Insoluble; Ethanol: 90 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CPI-1205 can be used to inhibit EZH2, a histone methyltransferase implicated in cancer.
