Properties
Description
CPI-360, soluble in warmed DMSO and warmed ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH2.
Molecular Formula
C25H31N3O4
Solubility
Warmed DMSO: 18 mg/mL (41.14 mM); Water: Insoluble; Warmed ethanol: 16 mg/mL (36.57 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CPI-360 can be used as a dual inhibitor of BET bromodomains and HMT G9a, targeting epigenetic regulation.
