Properties
Description
GNE-781, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription.
Molecular Formula
C27H33F2N7O2
Solubility
DMSO: 96 mg/mL (182.65 mM); Water: Insoluble; Ethanol: 96 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GNE-781 can be used to inhibit specific bromodomain, aiding in cancer and epigenetic studies.
