HMT inhibitor GNE-781, Purity ≥98%

Synonym: 1936422-33-1; GNE 781; GNE781; Histone methyltransferase inhibitor

CAS Number: 1936422-33-1
Compound CID: 132275066

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GNE-781, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription.

Molecular Weight

525.59

Molecular Formula

C₂₇H₃₃F₂N₇O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 96 mg/mL (182.65 mM); Water: Insoluble; Ethanol: 96 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

GNE-781 can be used to inhibit specific bromodomain, aiding in cancer and epigenetic studies.