HMT inhibitor GSK126, Purity ≥98%

Synonym: 1346574-57-9; GSK 126; GSK-126; Histone methyltransferase inhibitor

CAS Number: 1346574-57-9
Compound CID: 68210102

Product Size

2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK126, soluble in warmed DMSO and insoluble in water and ethanol, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH2.

Molecular Weight

526.67

Molecular Formula

C₃₁H₃₈N₆O₂

Targets

EZH2: 9.9 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 3 mg/mL (5.69 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK126 can be used to inhibit EZH2, resulting in modulation of histone H3K27 methylation.