HMT inhibitor GSK2807 trifluoroacetate, Purity ≥98%

Synonym: 2245255-66-5; GSK 2807; GSK-2807; Histone methyltransferase inhibitor

CAS Number: 2245255-66-5
Compound CID: 134814505

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK2807 trifluoroacetate inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets SMYD3 and SMYD3.

Molecular Weight

566.53

Molecular Formula

C₂₁H₃₃F₃N₈O₇

Targets

SMYD3: 14 nM (Ki); SMYD3: 130 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK2807 trifluoroacetate can be used as a selective inhibitor of PRMT5 for studying its role in cellular processes.

Storage

Store at -20ºC.