Properties
Description
GSK503, soluble in DMSO and warmed ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH2.
Molecular Formula
C31H38N6O2
Solubility
DMSO: 85 mg/mL (161.39 mM); Water: Insoluble; Warmed ethanol: 22 mg/mL (41.77 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GSK503 can be used to inhibit EZH2, impacting histone methylation and gene silencing mechanisms.
