Properties
Description
LLY-507, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets SMYD2.
Molecular Formula
C36H42N6O
Solubility
DMSO: 86 mg/mL (149.62 mM); Water: Insoluble; Ethanol: 19 mg/mL (33.05 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
LLY-507 can be used to inhibit PRMT5, providing insights into arginine methylation and gene expression.