HMT inhibitor MG149, Purity ≥98%

Synonym: 1243583-85-8; MG 149; MG-149; Histone methyltransferase inhibitor

CAS Number: 1243583-85-8
Compound CID: 49864204

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MG149, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription. It targets MOF and Tip60.

Molecular Weight

340.46

Molecular Formula

C₂₂H₂₈O₃

Targets

MOF: 47 μM; Tip60: 74 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 63 mg/mL (185.03 mM); Water: Insoluble; Ethanol: 63 mg/mL (185.03 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

MG149 can be used to inhibit histone acetyltransferases KAT5 and MOZ, useful in leukemia research.