HMT inhibitor MI-3, Purity ≥98%

Synonym: 1271738-59-0; Menin-MLL Inhibitor; Histone methyltransferase inhibitor

CAS Number: 1271738-59-0
Compound CID: 51001299

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MI-3, soluble in warmed DMSO and warmed ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets Menin-MLL.

Molecular Weight

375.55

Molecular Formula

C₁₈H₂₅N₅S₂

Targets

Menin-MLL: 648 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 17 mg/mL (45.26 mM); Water: Insoluble; Warmed ethanol: 17 mg/mL (45.26 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

MI-3 can be used to disrupt Menin-MLL binding, impacting epigenetic regulation in leukemia.

Storage

Store at -20ºC.