Properties
Description
OICR-9429, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression.
Molecular Formula
C29H32F3N5O3
Solubility
DMSO: 37 mg/mL (66.59 mM); Water: Insoluble; Ethanol: 14 mg/mL (25.19 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
OICR-9429 can be used as a chemical probe to study protein-protein interactions involving MLL1 and WDR5.
