HMT inhibitor PF-06726304, Purity ≥98%

Cat. No.: X24-05-ZQ533

HMT inhibitor PF-06726304, Purity ≥98%

Synonym: 1616287-82-1; PF 06726304; PF06726304; Histone methyltransferase inhibitor

  • CAS Number: 1616287-82-1
  • Compound CID: 86723730
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
PF-06726304, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH2 WT and EZH2 Y641N.
Molecular Weight
446.32
Molecular Formula
C22H21Cl2N3O3
Targets
EZH2 WT: 0.7 nM (Ki); EZH2 Y641N: 3 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 9 mg/mL (20.16 mM); Water: Insoluble; Ethanol: 20 mg/mL (44.81 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PF-06726304 can be used to inhibit CDK9 in cancer research, affecting transcription regulation.
Storage
Store at -20ºC.
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