Properties
Description
PFI-2 inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets SETD7 and SETD7.
Molecular Formula
C23H25F4N3O3S
Targets
SETD7: 0.33 nM (Ki); SETD7: 2 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PFI-2 can be used to inhibit the SETD7 methyltransferase, studying its role in cellular processes and disease.
