HMT inhibitor Remodelin hydrobromide, Purity ≥98%

Synonym: 1622921-15-6; Remodelin hydrobromide; Remodelin HBR; Remodelin (hydrobromide); 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile hydrobromide; Histone methyltransferase inhibitor

CAS Number: 1622921-15-6
Compound CID: 86280479

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Remodelin hydrobromide, soluble in warmed DMSO and insoluble in water and ethanol, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription. It targets Acetyl-transferase NAT10.

Molecular Weight

363.28

Molecular Formula

C₁₅H₁₅BrN₄S

Targets

Acetyl-transferase NAT10

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 63 mg/mL (173.42 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Remodelin hydrobromide can be used in progeria research to study the effects of acetyltransferase inhibition.

Storage

Store at -20ºC.