HMT inhibitor UNC0321, Purity ≥98%

Synonym: 1238673-32-9; UNC0321; UNC-0321; UNC 0321; 7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine; Histone methyltransferase inhibitor

CAS Number: 1238673-32-9
Compound CID: 46901937

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

UNC0321 inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EHMT1/GLP/KMT1D, G9a, and G9a.

Molecular Weight

515.69

Molecular Formula

C₂₇H₄₅N₇O₃

Targets

EHMT1/GLP/KMT1D: 15-23 nM; G9a: 63 pM (Ki); G9a: 6-9 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

UNC0321 can be used to examine the effects of G9a/GLP inhibition on chromatin and gene expression.