Properties
Description
UNC0379, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets SETD8.
Molecular Formula
C23H35N5O2
Solubility
DMSO: 79 mg/mL (191.02 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
UNC0379 can be used as a selective inhibitor of lysine methyltransferase G9a, exploring its role in epigenetics.
