HMT inhibitor UNC0646, Purity ≥98%

Synonym: 1320288-17-2; UNC 0646; UNC-0646; Histone methyltransferase inhibitor

CAS Number: 1320288-17-2
Compound CID: 53315882

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

UNC0646, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets G9a and GLP.

Molecular Weight

621.9

Molecular Formula

C₃₆H₅₉N₇O₂

Targets

G9a: 6 nM; GLP: <15 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 31 mg/mL (49.84 mM); Water: Insoluble; Ethanol: 47 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

UNC0646 can be used to study the biochemical and cellular roles of G9a inhibition in histone methylation.

Storage

Store at -20ºC.