Properties
Description
WM-1119, soluble in DMSO and insoluble in ethanol and water, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription.
Molecular Formula
C18H13F2N3O3S
Solubility
DMSO: 69 mg/mL (177.2 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
WM-1119 can be used to inhibit H3K27me3 demethylase KDM6 for epigenetic research.