Cat. No.: X22-05-ZQ392
Homoharringtonine
Synonym: 26833-87-4; Homoharringtonine; Omacetaxine mepesuccinate; 1-O-[(2S,3S,6R)-4-Methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2R)-2-Hydroxy-2-(4-Hydroxy-4-methylpentyl)butanedioate
- MDL: MFCD05618221
- CAS Number: 26833-87-4
- Compound CID: 285033
Product Size
10 mg; 20 mg; 50 mg; 100 mg
Properties
Description
Homoharringtonine, a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversibly inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression. This product can be used for research in the fields of medicine and pharmacy.
Molecular Formula
C29H39NO9
Purity
≥98%, determined by HPLC.
Solubility
It is hardly soluble in water, but easily soluble in methanol, ethanol, chloroform, ether and other organic solvents.
Identity
Confirmed by MS and NMR.
Applications
Homoharringtonine can be used for research in the fields of medicine and pharmacy.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
Related Products
