HSP inhibitor, Apoptozole, Purity ≥98%

Synonym: 1054543-47-3; Apoptosis activator VII; 4-[[2-[3,5-Bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)imidazol-1-yl]methyl]benzamide; HSP inhibitor

MDL: MFCD19443178
CAS Number: 1054543-47-3
Compound CID: 24894064

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Apoptozole, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 625.56, and its molecular formula is C₃₃H₂₅F₆N₃O₃. It targets the HSC70 and HSP70.

Molecular Weight

625.56

Molecular Formula

C₃₃H₂₅F₆N₃O₃

Targets

HSC70

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 96 mg/mL (153.46 mM); Water: insoluble; Ethanol: 24 mg/mL (38.36 mM); In vivo: 2% DMSO + 30% PEG 300 + 5% Tween 80 + ddH₂O, 4 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Apoptozole can be studied extensively for its potential therapeutic applications in the treatment of neurodegenerative diseases where Hsp70 plays a protective role.