Properties
Description
AUY922, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 465.5, and its molecular formula is C26H31N3O5. It targets the HSP90α (Cell-free assay) and HSP90β (Cell-free assay).
Molecular Formula
C26H31N3O5
Targets
HSP90α (Cell-free assay)
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 86 mg/mL (184.72 mM); Water: insoluble; Ethanol: 29 mg/mL (62.28 mM); In vivo: 1% DMSO + 30% polyethylene glycol + 1% Tween 80, 28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
AUY922 can be studied extensively for its potential therapeutic applications in the treatment of a wide range of cancer types, including breast, lung, and prostate cancers.
