Properties
Description
BIIB021, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 318.8, and its molecular formula is C14H15ClN6O. It targets the HSP90 and HSP90.
Molecular Formula
C14H15ClN6O
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 60 mg/mL (188.22 mM); Water: insoluble; Ethanol: 2 mg/mL (6.27 mM); In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
BIIB021 plays a key role in blocking the signaling pathways that promote cell survival, proliferation, and migration, thereby inhibiting tumor growth.
