Properties
Description
Elesclomol, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 400.5, and its molecular formula is C19H20N4O2S2.
Molecular Formula
C19H20N4O2S2
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 77 mg/mL (192.26 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG300 + 5% Tween80 + 50% H2O, 9 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Elesclomol plays a key role in interfering with DNA synthesis and inducing apoptosis in cancer cells.
