HSP inhibitor, Ganetespib, Purity ≥98%

Synonym: 888216-25-9; STA9090; STA9090; STA 9090; 3-(2,4-Dihydroxy-5-isopropylphenyl)-4-(1-methylindol-5-yl)-5-hydroxy-4H-1,2,4-triazole; 3-(2,4-Dihydroxy-5-propan-2-ylphenyl)-4-(1-methylindol-5-yl)-1H-1,2,4-triazol-5-one; HSP inhibitor

MDL: MFCD22420818
CAS Number: 888216-25-9
Compound CID: 135564985

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Ganetespib, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 364.4, and its molecular formula is C₂₀H₂₀N₄O₃. It targets the HSP90 (OSA 8 cells).

Molecular Weight

364.4

Molecular Formula

C₂₀H₂₀N₄O₃

Targets

HSP90 (OSA 8 cells)

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 37 mg/mL (101.53 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 45% PEG 300 + ddH₂O, 10 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Ganetespib can be studied extensively for its potential therapeutic applications in the treatment of various cancers, including lung cancer, breast cancer, and multiple myeloma.