Cat. No.: X24-09-YM067
HSP inhibitor, Geldanamycin, Purity ≥98%
Synonym: 30562-34-6; U-29135; [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate; HSP inhibitor
- MDL: MFCD00274570
- CAS Number: 30562-34-6
- Compound CID: 5288382
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
Geldanamycin, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 560.6, and its molecular formula is C29H40N2O9. It targets the HSP90, HSP90 (N-terminal domain) and p185.
Molecular Formula
C29H40N2O9
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 32 mg/mL (57.08 mM); Water: insoluble; Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Geldanamycin can be studied extensively for its potential therapeutic applications in the treatment of various cancers by destabilizing and degrading oncogenic client proteins, leading to the inhibition of tumor growth and progression.
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